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A 16-week randomized controlled trial evaluating the physical activity guidelines for adults with spinal cord injury
Pelletier CA, Totosy de Zepetnek JO, MacDonald MJ, Hicks AL
Spinal Cord 2015 May;53(5):363-367
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

STUDY DESIGN: Randomized controlled trial. OBJECTIVES: To evaluate the effectiveness of the physical activity guidelines (PAG) for adults with spinal cord injury (SCI) to improve aspects of physical fitness. SETTING: Community exercise facility. METHODS: Twenty-three participants (age 40.4 +/- 11.6 years, C1 to T11, 12.0 +/- 10.0 years post injury) were randomized into PAG training (n = 12) or active control (CON, n = 11) groups. PAG training was 2x per week for 16 weeks and involved 20 min of aerobic exercise at a moderate to vigorous intensity and three sets of 10 repetitions (at 50 to 70% 1 repetition maximum; 1RM). Pre- and post-testing included peak exercise and aerobic endurance tests on an arm ergometer and 1RM testing. RESULTS: Nineteen participants (PAG, n = 11; CON, n = 8) completed the 16-week training program and post-testing. There was a significant (p < 0.05) increase in peak aerobic capacity (relative VO2peak: 17.2%, absolute VO2peak: 9.9%) and submaximal power output (26.3%) in the PAG group only. Increases in strength ranged from 11.5 to 38.9% and were significantly (p < 0.05) different from CON for vertical bench press, seated row, and rickshaw press. Adherence to the exercise program was 85.2 +/- 8.3% for PAG, 44.4 +/- 34.3% for CON (p < 0.01). CONCLUSION: The PAG for adults with SCI are sufficient to improve aspects of aerobic and muscular fitness and should be promoted as a means to improve physical capacity. SPONSORSHIP: Ontario Neurotrauma Foundation (ONF), Natural Sciences and Engineering Research Council (NSERC) of Canada.
Reprinted by permission from Spinal Cord, Macmillan Publishers Ltd.

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