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The effect of subthreshold continuous electrical stimulation on the facial function of patients with Bell's palsy
Kim J, Choi JY
Acta Oto-Laryngologica 2016 Jan;136(1):100-105
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

CONCLUSION: The drug regimen plus electrical stimulation was more effective in treating Bell's palsy than the conventional drug treatment alone. The effectiveness of such a sub-threshold, continuous, low frequency electrical stimulation suggests a new therapeutic approach to accelerate nerve regeneration an improve functional recovery after injury. OBJECTIVES: The purpose of this study was to determine whether sub-threshold, continuous electrical stimulation at 20Hz facilitates functional recovery of patients with Bell's palsy. MATERIALS AND METHODS: The authors performed a prospective randomized study that included 60 patients with mild-to-moderate grade Bell's palsy (HB grade <= 4, SB grade >= 40), to evaluate the effect of developed electrical stimulation on the resolution of symptoms. Thirty patients were treated with prednisolone or/and acyclovir plus electrical stimulation within 7 days of the onset of symptoms. The other 30 patients were treated with only prednisolone or/and acyclovir as a control group. RESULTS: The overall rate of patient recovery among those treated with prednisolone or/and acyclovir plus electrical stimulation (96%) was significantly better (p < 0.05) than the rate among those treated with only prednisolone or/and acyclovir (88%).

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