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Randomised crossover study of the Flutter device and the active cycle of breathing technique in non-cystic fibrosis bronchiectasis
Thompson CS, Harrison S, Ashley J, Day K, Smith DL
Thorax 2002 May;57(5):446-448
clinical trial
3/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Airway clearance techniques are an important part of the routine care of patients with bronchiectasis. The use of the Flutter, a hand held pipe-like device causing oscillating positive expiratory pressure within the airways, has been proposed as an alternative to more conventional airway clearance techniques. patients with non-cystic fibrosis bronchiectasis at home, in which 4 weeks of daily active cycle of breathing technique (ACBT) were compared with 4 weeks of daily physiotherapy with the Flutter device. found. Median weekly sputum weights were similar with a median treatment difference of 7.64 g (p = 0.77) and there was no evidence of treatment order or order interaction effects (p = 0.70). Health status (Chronic Respiratory Disease Questionnaire) and ventilator function did not change significantly during either treatment period. There was no significant change in peak expiratory flow rate or in breathlessness (Borg score) after individual physiotherapy sessions with either technique. A questionnaire indicated subjectively that patients referred the Flutter (11/17) to ACBT for routine use. effective as ACBT in patients with non-cystic fibrosis bronchiectasis and has a high level of patient acceptability.
Reproduced with permission from the BMJ Publishing Group.

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