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Legochnaya reabilitatsiya kak effektivnyi metod optimizatsii lechebno-profilakticheskikh meropriyatii u bol'nykh khronicheskoi obstruktivnoi bolezn'yu legkikh s metabolicheskim sindromom (Pulmonary rehabilitation as an effective method for optimizing therapeutic and preventive measures in patients with chronic obstructive pulmonary disease concurrent with metabolic syndrome) [Russian]
Budnevsky AV, Isaeva YV, Malysh EY, Kozhevnikova SA
Terapevticheskii Arkhiv [Soviet Archives of Internal Medicine] 2016;88(8):25-29
clinical trial
2/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: No; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIM: To evaluate the impact of a pulmonary rehabilitation (PR) cycle based on patient education, smoking cessation, physical exercises, and balanced nutrition in addition to standard therapy for chronic obstructive pulmonary disease COPD in patients with this condition. SUBJECTS AND METHODS: 70 patients (27 (38.6%) women and 43 (61.4%) men) aged 18 to 60 years (mean age 48.31 +/- 0.64 years) with moderate COPD in remission concurrent with MS were examined. The comprehensive examination of the patients encompassed assessment of clinical, instrumental, and laboratory findings at baseline and 12 months. The patients were randomized into two groups: (1) 35 patients who underwent a RH cycle in addition to standard therapy for COPD; (2) 35 patients who received standard COPD treatment only. RESULTS: Group 1 was found to have significant differences in reducing the number of patients with COPD exacerbations, emergency calls, hospitalizations, severity of clinical symptoms of COPD and their impact on the physical activity and health of the patients, as well as better quality of life and exercise tolerance. CONCLUSION: The therapeutic and preventive measures for patients with COPD and MS should involve educational programs and physical trainings, which are developed, by taking into account of a comorbidity in order to optimize therapeutic and preventive measures and to improve quality of life in this category of patients.

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