BACKGROUND: Balance and walking impairments are frequent in people with multiple sclerosis (MS). OBJECTIVE: The aim was to investigate the effects of a group-based balance exercise program targeting core stability, dual tasking, and sensory strategies (CoDuSe) on balance, postural sway, walking, perceived walking limitations, and balance confidence. DESIGN: A single-blinded randomized multicenter trial. No intervention was given to controls. PARTICIPANTS: People with MS able to walk 100 meters but unable to maintain tandem stance > 30 seconds. Eighty-seven participants were randomized to intervention or control. Intervention. The 60-minute CoDuSe group program, twice weekly for seven weeks, supervised by physical therapists. MEASUREMENTS: Primary outcome was dynamic balance (Berg Balance Scale (BBS)). Secondary outcomes were postural sway, walking (Timed-Up and Go test; Functional Gait Assessment (FGA)), MS Walking Scale, and Activities-specific Balance Confidence (ABC) Scale. Assessments were performed before and after (week 8) the intervention. RESULTS: 73 participants fulfilled the study. There were significant differences between the intervention and the control groups in change in the BBS and in the secondary measures: postural sway with eyes open, FGA, MS Walking Scale, and ABC scale in favor of the intervention. CONCLUSIONS: The seven-week CoDuSe program improved dynamic balance more than no intervention.

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