BACKGROUND: Resistance training (RT) has been utilised to target muscle dysfunction associated with chronic heart failure (CHF). However, there is limited meta-analysis evidence to support its use as a standalone therapy. This meta-analysis examined the effects of RT on muscle strength (one repetition maximum, 1RM and peak torque), aerobic capacity (VO2peak and 6 min walk distance) and quality of life (QoL) in patients with CHF. METHODS: We searched Medline, Embase, Cochrane and CINAHL for studies published up to July 2016, combining terms related to the population (eg, heart failure, CHF) with terms for the intervention (eg, resistance, strength training) and the outcomes (eg, QoL, VO2peak, strength, aerobic capacity). RESULTS: Ten studies including 240 participants were included in our meta-analysis (aged 48 to 76 years, ejection fraction 18 to 37%). Training duration ranged from 8 to 24 weeks and intensity up to 80% of 1RM. RT increased 1RM (standardised change score 0.60; 95% confidence interval 0.43 to 0.77) but not strength measured via peak torque at 60 degrees/s and 180 degrees/s. RT increased VO2peak (CSMD 2.71 ml/kg/min; 1.96 to 3.45) and QoL (CSMD -5.71; -9.85 to -1.56). CONCLUSION: RT as a single intervention can increase muscle strength, aerobic capacity and QoL in patients with CHF and may offer an alternative approach, particularly for those unable to participate in aerobic training. The effect of RT on muscle strength is mainly during slow controlled movements and not during rapid movements. Older adults and patients with advanced CHF are underrepresented in RT trials and future studies should seek to optimise their inclusion.

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