A meta-analysis on active video games (AVG) as a rehabilitative tool does not appear to be available. This meta-analytic review synthesizes the effectiveness of AVGs on patients' rehabilitative outcomes. Ninety-eight published studies on AVGs and rehabilitation were obtained in late 2015 with 14 meeting the following inclusion criteria: (1) data-based English articles; (2) randomized-controlled trials investigating AVG's effect on rehabilitative outcome(s); and (3) > 1 comparison present in each study. Data extraction for comparisons was completed for three age categories: (1) youth/young adults (5 to 25 years-old); (2) middle-aged adults (40 to 65 years-old); and (3) older adults (> 65 years-old). Comprehensive Meta-Analysis software calculated effect size (ES; Hedge's g). Comparison group protocols often employed another non-AVG experimental treatment. Control group protocols implemented standard care. AVGs demonstrated a large positive effect on balance control over control among youth/young adults (ES = 0.81, p < 0.01). Further, AVGs resulted in small positive effects on middle-aged adults' balance control over control (ES = 0.143, p = 0.48) and comparison (ES = 0.14, p = 0.53), with similar results in older adults compared to control (ES = 0.16, p = 0.27). Notably, AVG's effect on balance control versus comparison among older adults was small yet negative (ES = -0.12, p = 0.63). AVGs were also used to enhance general physical functioning (GPF) among middle-aged and older adults. Versus control and comparison, AVGs had no effect on middle-aged adults' GPF (ES = -0.054 and -0.046, respectively) or older adults' GPF (ES = 0.04 and 0.002, respectively). Finally, AVGs had a moderate effect on older adults' falls efficacy versus control (ES = 0.61, p < 0.05). Findings favor AVGs for youth/young adult balance control rehabilitation and falls efficacy promotion in older adults.
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