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Benefits of exercise on the executive functions in people with Parkinson disease: a controlled clinical trial |
de Oliveira RT, Felippe LA, Bucken Gobbi LT, Barbieri FA, Christofoletti G |
American Journal of Physical Medicine & Rehabilitation 2017 May;96(5):301-306 |
clinical trial |
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
OBJECTIVE: We have made a 3-arm trial (group versus individual exercise versus no treatment) to test the effects of a 6-month exercise program upon the executive functions in participants with Parkinson disease. METHODS: Twenty-four subjects were randomly allocated in 3 groups and undertook individualized exercises (G1, n = 8), group exercises (G2, n = 8), or monitoring (G3, n = 8). Executive functions were evaluated by means of the Wisconsin card sorting test and the Raven colored matrices, both assessed at the beginning of the program and after 6 months. The statistical analyses consisted of the application of repeated measurement tests, with a significant level of 5%. RESULTS: The findings showed similar behavior of groups in terms of the Wisconsin card sorting test (p = 0.792), reporting no benefit of the program on such instrument. Differently, Raven colored matrices evidenced a significant benefit provided by the intervention (p = 0.032). Compared with the control group, individuals from G1 had a substantial improvement on executive functions (p = 0.031) and from G2 had a trend of significance (p = 0.072). CONCLUSION: Findings of this study show that 6 months of exercise improved some aspects of executive functions when compared with control peers. Individual therapy seems to have a more prominent improvement than group therapy.
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