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Four-year physical activity levels among intervention participants with type 2 diabetes
Unick JL, Gaussoin SA, Hill JO, Jakicic JM, Bond DS, Hellgren M, Johnson KC, Peters AL, Coday M, Kitzman DW, Bossart S, Wing RR
Medicine and Science in Sports and Exercise 2016 Dec;48(12):2437-2445
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Physical activity (PA) has numerous health benefits, particularly for those with diabetes. However, rates of long-term PA participation are often poor. PURPOSE: This study examined the effect of an intensive lifestyle intervention (ILI) on objectively assessed PA for a 4-yr period among older adults with type 2 diabetes. METHODS: Data from 2,400 participants (age 59.3 +/- 6.9 yr, body mass index 36.1 +/- 5.9 kg/m2) with accelerometry data from the Look AHEAD trial were included in the analyses. Participants randomized to ILI were instructed to reduce caloric intake and progress to >= 175 min/wk of moderate-to-vigorous-intensity PA (MVPA), whereas those randomized to Diabetes Support and Education (DSE) served as the control group. PA was measured at baseline, year 1, and year 4 using an RT3 accelerometer, and bout-related MVPA (PA >= 3 METs, accumulated in bouts of >= 10 min in duration) was calculated. RESULTS: Despite no differences at baseline (ILI 93.4 +/- 152.7 versus DSE 88.4 +/- 143.6 min/wk), bout-related MVPA was significantly greater in ILI compared with DSE at year 1 (151.0 +/- 213.5 versus 87.5 +/- 145.1 min/wk, p < 0.0001) and year 4 (102.9 +/- 195.6 versus 73.9 +/- 267.5 min/wk, p < 0.001), and more ILI participants achieved >= 175 min/wk at year 1 (29.1% versus 16.3%, p < 0.001) and year 4 (18.3% versus 10.0%, p < 0.001). Forty-one percent of ILI participants who achieved >= 175 min/wk at year 1 maintained this threshold of PA at year 4. However, the majority of ILI participants never achieved the >= 175 min/wk threshold. CONCLUSIONS: When measured objectively and compared with DSE, ILI engaged in significantly more bout-related MVPA for a 4-yr period. However, future intervention strategies should target the large percentage of individuals who fail to reach the MVPA goal as result of a lifestyle intervention.

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