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The impact of reduced cardiac rehabilitation on maximal treadmill exercise time: a randomized controlled trial
Farias-Godoy A, Chan S, Claydon VE, Ignaszewski A, Mendell J, Park JE, Singer J, Lear SA
Journal of Cardiopulmonary Rehabilitation and Prevention 2018 Jan;38(1):24-30
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

PURPOSE: Cardiac rehabilitation programs (CRPs) remain underutilized partly because of access barriers. We therefore evaluated a CRP with fewer center-based sessions (rCRP) compared with standard CRP (sCRP) with respect to changes in exercise capacity and cardiac risk factors. METHODS: In this randomized controlled noninferiority trial, primary and secondary prevention patients at low and moderate risk were randomized to an sCRP (n = 60) or an rCRP (n = 61). Over 4 months, sCRP and rCRP participants attended 32 and 10 on-site cardiac rehabilitation sessions, respectively. The primary outcome was the difference in the change in exercise capacity from baseline at 4 and 16 months between the groups measured in seconds from a maximal treadmill exercise test. Noninferiority of the rCRP was tested with mixed-effects model analysis with a cut point of 60 seconds for the upper value of the group estimate. RESULTS: Attendance was higher for the rCRP group (97% +/- 63% versus 71% +/- 22%, p = 0.002). Over 16 months, exercise test time increased for the sCRP (524 +/- 168 to 604 +/- 172 seconds, p < 0.01) and the rCRP (565 +/- 183 to 640 +/- 192 seconds, p < 0.01). The rCRP was not inferior to the sCRP regarding changes in treadmill time (48.47 seconds, p = 0.454). The rCRP was not inferior to the sCRP regarding metabolic and anthropometric risk factors. CONCLUSION: Our findings suggest that, for a selected group of low-/moderate-risk patients, the number of center-based CRP exercise sessions can be decreased while maintaining reduced cardiovascular risk factors.
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