Use the Back button in your browser to see the other results of your search or to select another record.
Detailed Search Results
| Treatment adherence in child and adolescent chronic migraine patients: results from the cognitive-behavioral therapy and amitriptyline trial |
| Kroon van Diest AM, Ramsey RR, Kashikar-Zuck S, Slater S, Hommel K, Kroner JW, le Cates S, Kabbouche MA, O'Brien HL, Kacperski J, Allen JR, Peugh J, Hershey AD, Powers SW |
| The Clinical Journal of Pain 2017 Oct;33(10):892-898 |
| clinical trial |
| 4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
|
OBJECTIVES: To examine treatment adherence among children and adolescents with chronic migraine who volunteered to be in a clinical trial using 3 measures: treatment session attendance, therapy homework completion, and preventive medication use by daily diary. MATERIALS AND METHODS: Analyses are secondary from a trial of 135 youth aged 10 to 17 years diagnosed with chronic migraine and with a Pediatric Migraine Disability Score over 20. Participants were randomly assigned to cognitive-behavioral therapy plus amitriptyline (CBT+A, n = 64) or headache education plus amitriptyline (HE+A, n = 71). Therapists recorded session attendance. Completion of homework/practice between sessions was reported to therapists by patients. Patients reported preventive medication adherence using a daily headache diary. RESULTS: Mean session attendance adherence out of 10 treatment sessions was 95% for CBT+A and 99% for HE+A. CBT+A participants reported completing a mean of 90% of home practice of CBT skills between the 10 sessions. Participants reported taking amitriptyline daily at a mean level of 90% when missing diaries were excluded and 79% when missing diaries were considered as missed doses of medication. DISCUSSION: Our findings demonstrate that youth with chronic migraine who agree to be a part of a clinical trial do quite well at attending therapy sessions, and report that they are adherent to completing home/practice between sessions and taking medication. These results lend further support to consideration of CBT+A as a first-line treatment for youth with chronic migraine and suggest that measurement of adherence when this treatment is provided in practice will be important.
|
The database was last updated on 5 May 2025 (this includes records added or amended since 7 April 2025). The next update is planned for 2 June 2025. The total number of records on the database is 65,032.