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Impact of Mezieres rehabilitative method in patients with Parkinson's disease: a randomized controlled trial
Paolucci T, Zangrando F, Piccinini G, Deidda L, Basile R, Bruno E, Buzi E, Mannocci A, Tirinelli F, Haggiag S, Lispi L, Villani C, Saraceni VM
Parkinson's Disease 2017 Dec 3;(2762987):Epub
clinical trial
8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The aim of this study was to assess the efficacy of Mezieres method in improving trunk flexibility of the back muscles and balance in patients with Parkinson's disease (PD). MATERIALS AND METHODS: Thirty-six patients were randomized into 2 groups: the Mezieres treatment group and the control group (home exercise group). The primary outcome was the improvement in balance per the Berg Balance Scale (BBS) and the trunk flexibility of the back for the anterior flexion trunk test. Also, we evaluated pain, gait balance for the Functional Gait Assessment (FGA), disease-related disability for the Modified Parkinson's Activity Scale and the Unified Parkinson's Disease Rating Scale (UPDRS), the quality of life, and the functional exercise capacity. All the measures were evaluated at baseline (T0), at the end of the rehabilitative program (T1), and at the 12-week follow-up (T2). RESULTS: In the Mezieres group, the BBS (p < 0.001) and trunk flexion test (p < 0.001) improved significantly at T1 and remained the same at T2. Between groups, significant changes were reported in FGA (p = 0.027) and UPDRS Total (p = 0.007) at T1 and in FGA (p = 0.03) at T2. CONCLUSION: The Mezieres approach is efficacious in improving the flexibility of the trunk and balance in PD patients.

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