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Randomized controlled trial in advance stage breast cancer patients for the effectiveness on stress marker and pain through Sudarshan Kriya and Pranayam
Kumar N, Bhatnagar S, Velpandian T, Patnaik S, Menon G, Mehta M, Kashyap K, Singh V, Surajpal
Indian Journal of Palliative Care 2013 Sep-Dec;19(3):180-185
clinical trial
6/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: The objective of this study is to examine the effect of a cognitive, behavioral stress management module of Sudarshan Kriya (SK) and P on levels of serum cortisol and pain among the women suffering from advanced stage breast cancer. MATERIALS AND METHODS: Participants (n = 147) were screened and randomized to receive standard care (n = 69) versus standard along with SK and Pranayam (P) intervention (n = 78) imparted in one 18 hrs workshop spread during 3 days. Participants were expected to practice it at home 20 min daily as adjuvant to standard pharmacological treatment for pain. RESULTS: There was a significant difference in blood cortisol levels after 3 months of practice of SK and p. Mean blood levels in the intervention arm were 341.2 ng/ml against 549.2 ng/ml in the control arm (p <= 0.002). Pain perception in comparison to control arm reduced by 3 points in SK and P arm on 0 to 10 verbal scale of pain. CONCLUSION: SK and P is an effective intervention in reducing stress and pain among advance stage patients of breast cancer.

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