Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

Effects of active commuting and leisure-time exercise on fat loss in women and men with overweight and obesity: a randomized controlled trial
Quist JS, Rosenkilde M, Petersen MB, Gram AS, Sjodin A, Stallknecht B
International Journal of Obesity 2018 Mar;42(3):469-478
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Aerobic exercise is recommended for weight management but energy balance is often less negative than predicted from exercise energy expenditure (ExEE). OBJECTIVE: To examine effects of active commuting and leisure-time exercise on fat loss in women and men with overweight and obesity. METHODS: We randomized 130 younger, physically inactive women and men with overweight and obesity (body mass index 25 to 35kg/m2) to 6 months of habitual lifestyle (control; CON, n = 18), active commuting (BIKE, n = 35) or leisure-time exercise of moderate (MOD, 50% VO2peak reserve, n = 39) or vigorous intensity (VIG, 70% VO2peak reserve, n = 38). The primary outcome was change in fat mass measured by dual-energy x-ray absorptiometry, which was analyzed intention-to-treat. Accumulated energy balance was calculated based on changes in body composition, and ExEE was calculated based on heart rate monitoring during exercise. RESULTS: Testing at 3 and 6 months was completed by 95 and 90 participants, respectively. Fat mass was reduced after 3 and 6 months in BIKE (3 months -3.6 kg (-5.5 to -1.7) (mean (95% CI)); 6 months -4.2 kg (-6.6 to -1.9); both p < 0.001), MOD (3 months -2.2 kg (-3.9 to -0.4); 6 months -2.6 kg (-4.8 to -0.5), both p < 0.02) and VIG (3 months -3.4 kg (-5.2 to -1.7); 6 months -4.5 kg (-6.6 to -2.3); both p < 0.001) compared with CON. Furthermore, fat loss was greater in VIG compared with MOD (6 months -1.8 kg (-3.6 to -0.1), p = 0.043). Based on the ExEE and the accumulated energy balance MOD compensated for the ExEE (77% (48 to 106)) but not BIKE (38% (-18 to 95)) and VIG (21% (-14 to 55)). CONCLUSIONS: A meaningful fat loss was obtained by 6 months of active commuting and leisure-time exercise, but fat loss was greater with vigorous compared with moderate intensity exercise. Active commuting is an alternative to leisure-time exercise in the management of overweight and obesity. The trial was registered at ClinicalTrials.gov as NCT01962259 (main trial) and NCT01973686 (energy metabolism sub-study).

Full text (sometimes free) may be available at these link(s):      help