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Feasibility of a postacute structured aerobic exercise intervention following sport concussion in symptomatic adolescents: a randomised controlled study [with consumer summary]
Micay R, Richards D, Hutchison MG
BMJ Open Sport & Exercise Medicine 2018;4(1):e000404
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: The utility of structured exercise for rehabilitation purposes early in the postacute phase (ie, beyond the initial 24 to 48 hours of advised rest) following sport-related concussion (SRC) remains largely unexplored. This study examined the feasibility of implementing a standardised aerobic exercise (AE) intervention in the postacute stage of SRC recovery in a sample of adolescent students with SRC compared with usual care. METHODS: Symptomatic adolescents with SRC were randomised to one of two groups: aerobic exercise (n = 8) or usual care (n = 7). The AE intervention, beginning on day 6 postinjury, comprised eight sessions with progressive increases in intensity and duration on a cycle ergometer. Usual care consisted of rest followed by physician-advised progressions in activity levels in an unsupervised setting. All participants were evaluated by physician at weeks 1, 2, 3 and 4 postconcussion. Outcome measures included: (1) intervention feasibility: symptom status pre-post exercise sessions and completion of intervention and (2) clinical recovery: symptom status at weeks 1, 2, 3 and 4 postinjury and medical clearance date. RESULTS: All participants completed the exercise sessions as part of the AE intervention and symptom exacerbation was not associated with any exercise session. The AE group experienced greater symptom resolution compared with the usual care group across the recovery timeline. CONCLUSION: A structured AE protocol appears to be safe and feasible to administer in the postacute stage of SRC recovery in adolescents and should be explored as part of a full phase III clinical trial.

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