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Musical dual-task training in patients with mild-to-moderate dementia: a randomized controlled trial
Chen Y-L, Pei Y-C
Neuropsychiatric Disease and Treatment 2018 May 30;14:1381-1393
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND/AIMS: Dual-task training may improve dual-task gait performance, balance, and cognition in older adults with and without cognitive impairment. Although music has been widely utilized in dementia management, there are no existing protocols for music-based dual-task training. This randomized controlled study developed a Musical Dual-Task Training (MDTT) protocol that patients with dementia can use to practice walking and making music simultaneously, to enhance attention control in patients during dual-tasking. METHODS: Twenty-eight adults diagnosed with mild-to-moderate dementia were assigned to the MDTT (n = 15) or control groups (n = 13). The MDTT group received MDTT, while the control group participated in non-musical cognitive and walking activities. The effects of MDTT were evaluated through the primary outcome of attention control, and secondary outcomes of dual-task performance, balance, falls efficacy, and agitation. RESULTS: The MDTT group showed a significant improvement in attention control, while the control group did not (p < 0.001). A significant effect favored MDTT over control treatment for the secondary outcome of falls efficacy (p = 0.02) and agitation (p < 0.01). CONCLUSION: MDTT, a music therapy intervention that demands a high level of cognitive processing, enhances attention control, falls efficacy, and helps alleviate agitation in patients with mild-to-moderate dementia.

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