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Cardiac rehabilitation and physical activity: systematic review and meta-analysis
Dibben GO, Dalal HM, Taylor RS, Doherty P, Tang LH, Hillsdon M
Heart 2018 Sep;104(17):1394-1402
systematic review

OBJECTIVE: To undertake a systematic review and meta-analysis to assess the impact of cardiac rehabilitation (CR) on physical activity (PA) levels of patients with heart disease and the methodological quality of these studies. METHODS: Databases (Medline, Embase, CENTRAL, CINAHL, PsycINFO and SportDiscus) were searched without language restriction from inception to January 2017 for randomised controlled trials (RCTs) comparing CR to usual care control in adults with heart failure (HF) or coronary heart disease (CHD) and measuring PA subjectively or objectively. The direction of PA difference between CR and control was summarised using vote counting (ie, counting the positive, negative and non-significant results) and meta-analysis. RESULTS: Forty RCTs (6,480 patients: 5,825 CHD, 655 HF) were included with 26% (38/145) PA results showing a statistically significant improvement in PA levels with CR compared with control. This pattern of results appeared consistent regardless of type of CR intervention (comprehensive versus exercise-only) or PA measurement (objective versus subjective). Meta-analysis showed PA increases in the metrics of steps/day (1,423, 95% CI 757.07 to 2,089.43, p < 0.0001) and proportion of patients categorised as physically active (relative risk 1.55, 95% CI 1.19 to 2.02, p = 0.001). The included trials were at high risk of bias, and the quality of the PA assessment and reporting was relatively poor. CONCLUSION: Overall, there is moderate evidence of an increase in PA with CR participation compared with control. High-quality trials are required, with robust PA measurement and data analysis methods, to assess if CR definitely leads to important improvements in PA. Registered on PROSPERO (CRD42017055137).
Reproduced with permission from the BMJ Publishing Group.

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