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Effects of moderate- and high-intensity aerobic training program in ambulatory subjects with incomplete spinal cord injury -- a randomized controlled trial
Wouda MF, Lundgaard E, Becker F, Strom V
Spinal Cord 2018 Oct;56(10):955-963
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

STUDY DESIGN: Randomized controlled trial. OBJECTIVES: To investigate if high-intensity interval training (HIIT) exhibits a higher increase in physical capacity and activity levels compared to moderate-intensity training (MIT) and treatment as usual. SETTING: Sunnaas Rehabilitation Hospital. METHODS: Thirty ambulatory participants with incomplete spinal cord injury (SCI) were recruited at discharge from inpatient rehabilitation. Two intervention groups performed a 12-week individual training program at home by walking or running, depending on their physical ability. The MIT group was instructed to exercise three times a week at 70% of maximal heart rate (HRmax), while the HIIT group was instructed to exercise twice a week at 85 to 95% of HRmax. The control group received treatment as usual. Pre- and post-tests consisted of maximal exercise testing on a treadmill (peak oxygen uptake (peak VO2)), a 6-min walking test (6MWT), and 7 days of continuously activity monitoring (total daily energy expenditure (TDEE) and daily number of steps). RESULTS: The HIIT, MIT, and control groups showed an increase in peak VO2 from pre- to post-test. However, no between-group difference in physical capacity (peak VO2 and 6MWT) and physical activity levels (TDEE and daily number of steps) were found between these groups. CONCLUSIONS: Performing HIIT did not exhibit a greater increase in physical capacity and activity levels than performing MIT or "treatment as usual" in ambulatory participants with SCI. Further studies are needed to elucidate both short- and long-term effects of HIIT and MIT in this SCI subpopulation.
Reprinted by permission from Spinal Cord, Macmillan Publishers Ltd.

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