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Effects of cardiac rehabilitation Qigong exercise in patients with stable coronary artery disease undergoing phase III rehabilitation: a randomized controlled trial
Zhao F, Lin Y, Zhai L, Gao C, Zhang J, Ye Q, Zaslawski CJ, Ma F, Wang Y, Liang C
Journal of Traditional Chinese Medical Sciences 2018 Oct;5(4):420-430
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To explore the effectiveness and safety of cardiac rehabilitation Qigong exercise in stable coronary artery disease (CAD) patients undergoing phase III rehabilitation. METHOD(S): This was a randomized controlled trial. A total of 59 stable CAD patients undergoing phase III rehabilitation treated in sports medicine hospital from March 2017 to September 2017 were enrolled after meeting the inclusion criteria and then divided into cardiac rehabilitation Qigong exercise group (n = 30) receiving a 12-week intervention and control group (n = 29). All participants were assessed at baseline and at 12-week intervention for the primary outcome, that was treadmill test parameter and the secondary outcomes including physical fitness, body composition, bone mineral density, and cardiac ultrasound B-mode imaging. RESULT(S): There were no significant differences in baseline demographics between the two groups. After a 12-week cardiac rehabilitation Qigong exercise intervention, compared with the control group, deltaVO2 (initial 1,352.63 +/- 340.95 versus 12 weeks 1,594.57 +/- 467.14) versus (initial 1,363.83 +/- 322.90 versus 12 weeks 1,323.76 +/- 318.92) (p = 0.003), deltaVO2/kg (initial 21.23 +/- 3.56 versus 12 weeks 24.75 +/- 5.11) versus (initial 21.01 +/- 3.71 versus 12 weeks 20.35 +/- 3.66) (p = 0.002), deltaMETS (initial 6.19 +/- 1.12 versus 12 weeks 7.16 +/- 1.60) versus (initial 6.00 +/- 1.19 versus 12 weeks 5.86 +/- 1.23) (p = 0.001), deltaVO2/HR (p = 0.027), deltaSV (p = 0.014), deltaOUES (p = 0.012), delta-hand-grip strength (p = 0.002), delta-flexibility (p = 0.001), delta- balance (p = 0.002), delta-AT-score (p = 0.042), deltaBQI (p = 0.018). However, delta-resting systolic blood pressure (p = 0.004) and delta-resting diastolic pressure (p = 0.012) decreased in the cardiac rehabilitation Qigong exercise group. CONCLUSION(S): Cardiac rehabilitation Qigong exercise can improve cardiopulmonary aerobic capacity, physical fitness, bone mineral density in patients with stable CAD, suggesting that certain effect and safety for stable CAD patients undergoing phase III rehabilitation can be obtained.

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