OBJECTIVE: To evaluate the cost-utility of a lifestyle intervention among adolescents and young adults with cerebral palsy. DESIGN: Single-blind, randomized controlled trial. SETTING: Six university hospital/clinics in the Netherlands. PARTICIPANTS: Fifty-seven adolescents and young adults with spastic cerebral palsy classified as Gross Motor Functioning Classification System (GMFCS) level I to IV. INTERVENTION: A 6-month lifestyle intervention consisting of physical fitness training combined with counselling sessions focusing on physical behaviour and sports participation. MAIN OUTCOME MEASURES: Data on quality of life, direct medical costs and productivity costs were collected using standardized questionnaires. Quality adjusted life years (QALYs) were derived from the Short-Form 36 questionnaire using the Short-Form 6D. RESULTS: Quality of life remained stable over time for both groups. No significant differences between groups were found for direct medical costs or productivity costs. A cost-utility ratio of -23,664 per QALY was found for the lifestyle intervention compared with no treatment. CONCLUSION: The results of this study are exploratory, but indicate that implementing a lifestyle intervention for the cerebral palsy population might be cost-effective or cost-saving compared with offering no intervention to improve physical behaviour and fitness. However, the large range of uncertainty for the cost-utility ratio should be taken into account and the results interpreted with caution.

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