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| Effect of patient education and physical training on quality of life and physical exercise capacity in patients with paroxysmal or persistent atrial fibrillation: a randomized study [with consumer summary] |
| Joensen AM, Dinesen PT, Svendsen LT, Hoejbjerg TK, Fjerbaek A, Andreasen J, Sottrup MB, Lundbye-Christensen S, Vadmann H, Riahi S |
| Journal of Rehabilitation Medicine 2019 Jun;51(6):442-450 |
| clinical trial |
| 6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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OBJECTIVE: To examine the effect of a rehabilitation programme on quality of life and physical capacity in patients with atrial fibrillation. METHODS: Patients with paroxysmal and persistent atrial fibrillation were randomized to either a 12-week rehabilitation programme with education and physical training (intervention group) or standard care (control group). At baseline, after 3, 6 and 12 months participants completed 5 different quality of life questionnaires (AF-QoL-18, AFEQT, PHQ-9, GAD-7 and EQ-5D), and physical exercise tests. Differences in average) scores between groups were analysed by repeated measures analysis of variance (ANOVA). RESULTS: Fifty-eight patients (age range 43 to 78 years, 31% female) were included. In the intervention group the AF-QoL-18 score increased from baseline (48.4 (standard deviation (SD) 22.8)) to 6 months (68.0 (15.2)) compared with the control group (baseline 51.6 (22.3), 6 months 59.2 (27.3)). After 12 months, there was no difference. Similar patterns were found for the other questionnaires. Maximum exercise capacity improved in the intervention group from baseline (176 W (48)) to 6 months (190 W (55)). There was no change in the control group. CONCLUSION: Education and physical training may have a short-term (but no long-term) beneficial effect on quality of life and physical exercise capacity in patients with atrial fibrillation.
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