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Investigating the impact of eight weeks of aerobic and resistance training on blood lipid profile in elderly with non-alcoholic fatty liver disease: a randomized clinical trial
Ghamarchehreh ME, Shamsoddini A, Alavian SM
Gastroenterology and Hepatology from Bed to Bench 2019 Summer;12(3):190-196
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIM: The aim of this study was to investigate the effects of eight weeks aerobic and resistance exercise on blood lipid profile in elderly with non-alcoholic fatty liver disease (NAFLD). BACKGROUND(S): Increased sedentary have a potential role in the development of NAFLD. Exercise training as an effective strategy to reduce NAFLD is presented. METHOD(S): In a randomized clinical trial study, thirty nine elderly patients with NAFLD were enrolled and were randomly divided in three groups. Aerobic groups (AG n = 13), resistance group (RG n = 13) and control group (CG n = 13). AG participated in an 8-week aerobic training (three 45-min sessions per week at 55 to 75% of HRR (heart rate reserve)). RG participated in an 8-week resistance exercises (three 45-min sessions per week at 50 to 70% of 1RM (one-repetition measure). Blood lipid profile of patients were evaluated baseline and after eight weeks. RESULT(S): At baseline, there were no differences between the two groups. In two group, cholesterol and low density lipoprotein (LDL) of blood of elderly follow eight weeks aerobic training with p = 0.02 and p = 0.02 were decreased, respectively. Also, High density lipoprotein (HDL) was improved follow aerobic training (p = 0.008). However, the aerobic and resistance training were not effective on triglyceride (TG). CONCLUSION(S): aerobic training was more effective than resistance training in improving the blood lipid profile in elderly with NAFLD and can role in management of this condition.

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