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A study on efficacy of respiratory exercises coupled with neurodevelopmental treatment on pulmonary function of children with spastic quadriplegic cerebral palsy
Santhosh Kanna BS, Balabaskar K
Biomedical & Pharmacology Journal 2019;12(3):1519-1524
clinical trial
3/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Cerebral palsy is a group of condition characterized by motor dysfunction due to non-progressive brain damage early in life. They may also have decreased mobility, restriction in physical activity and limitation in functional capacities. Along with motor dysfunction, children with cerebral palsy can have abnormality of respiratory function. This study was intended to study the efficacy of respiratory exercises along with neurodevelopmental treatment in pulmonary function of children with spastic quadriplegic cerebral palsy. From the special school of NIEPMD, 30 children with spastic quadriplegic cerebral palsy who met the inclusion and exclusion criteria was selected. They were randomly allocated into 2 groups. Group A (control group) consists of 15 participants who were given neurodevelopmental therapy for 45 minutes, 5 days in a week for 6 weeks. Group B (experimental group) consists of 15 participants who were given neurodevelopmental treatment along with respiratory exercises for 45 minutes (30 min and 15 min), 5 days in a week for 6 weeks. Informed consent is obtained from the parents of the participants. Pre and post values of FVC, FEV1, FEV1/FVE% and PEF were obtained using pulmonary function tests and statistical analysis was done. Paired-t test value of pretest and post-test of FEV1 and FVC shows statistically very significant (p < 0.01) and FEV1/FVC % and PEF shows statistically significant (p < 0.05) in experimental group. The results on analysis between groups on improvement of FVC, FEV1, FEV1/FVC% and PEF shows significant improvement by independent sample t test value (p < 0.05). From the result of this study, it was concluded that respiratory exercises along with NDT is more effective on improving the lung function in children with spastic quadriplegic cerebral palsy than that of conventional NDT program alone.

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