OBJECTIVES: This study aims to investigate the effects of adding whole-body vibration (WBV) exercise to squat training (ST) on the physical function and muscle strength of patients with knee osteoarthritis (KOA). METHODS: 41 participants completed the intervention and measurements (ST group n = 21, age 65.00 +/- 4.39 years, BMI 23.01 +/- 2.95 kg/m2; WBV+ST group n = 20, age 64.10 +/- 4.95 years, BMI 24.79 +/- 3.12 kg/m2). The supervised eight-week intervention was performed three times per week with the intensity and duration increased gradually. Visual analog scale, Timed Up and Go test (TUG), 6-min Walk Distance test, and isokinetic measurements were performed at baseline and post-intervention. RESULTS: The peak torque (PT) of the extensors at 180 degrees/s increased significantly in the WBV+ST group compared with the ST group (p = 0.046). The peak work of the extensors and the PT of the flexors at 180 degrees/s improved only in the WBV+ST group (p < 0.0125). However, no significant changes in these variables were found between groups (p > 0.05). CONCLUSIONS: Adding 8 weeks of WBV training to ST can more effectively improve the muscular strength of knee extensors compared with ST in patients with KOA.

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