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(Evaluation of the efficiency and safety of magnet therapy for osteoarthritis. Results of the multicenter blind placebo-controlled study COSMO (Clinical evaluation of current magnet therapy for osteoarthritis)) [Russian]
Karateev AE, Pogozheva EY, Sukhareva ML, Lila AM, Ivanov AV, Osnovina IP, Shchashkova OV, Borisova SV, Larinsky NE, Israelyan Yu A, Afoshin SA, Bondarenko TP, Repchanskaya EA, Chernyavskaya LA, Pupina SP, Darmova TV
Nauchno-Prakticheskaya Revmatologiya [Rheumatology Science and Practice] 2020;58(1):55-61
clinical trial
4/10 [Eligibility criteria: No; Random allocation: No; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: Yes; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Magnet therapy (MT) is a well-known physiotherapy technique that is widely used to treat knee osteoarthritis (OA). OBJECTIVE(S): to determine the efficiency and safety of MT for knee OA. SUBJECTS AND METHODS: A study group consisted of 231 patients with knee OA (77.9% were women; mean age 61.9 +/- 12.2 years; body mass index 30.6 +/- 5.8 kg/m2; median disease duration 5.0 (2.0 to 10.0) years). The patients were randomly assigned to two groups. Group 1 patients received MT with an ALMAG+ device for 14 days; group 2 had false MT with a completely imitating ALMAG+ device that failed to create a magnetic field. The investigators evaluated the changes of the WOMAC index, pain intensity at rest and during movement on a 100 mm visual analogue scale (VAS), the need for nonsteroidal anti-inflammatory drugs (NSAIDs), and the degree of improvement, as assessed by patients (on a 5-point scale). RESULTS AND DISCUSSION: During the therapy, there was a statistically significant pain and stiffness reduction and functional improvement. Thus, there were decreases in the median WOMAC pain scores from 231 (180 to 290) to 110 (60 to 166.3) (p < 0.001) in group 1, from 212.4 (145 to 260) to 143 (76.5 to 200) (p < 0.001) in group 2, in pain intensity at rest from 47 (27.8 to 60) to 20 (10 to 30) mm (p < 0.001) in group 1; from 40 (20 to 57.5) to 20 (7.5 to 40) mm (p < 0.001) in group 2. During the therapy, there was also a reduction in the need for NSAIDs: the drug was discontinued or its dose reduced in 33.1% and 16.8% of the patients in groups 1 and 2, respectively (p = 0.006). The changes of all parameters were statistically more significant in group 1 than in group 2. Treatment results were assessed as good and excellent by 58.5% and 39.8% patients in groups 1 and 2, respectively (p < 0.001). No serious adverse events to true and false MT were observed. Therapy was discontinued due to increase of joint pain in two patients who received false MT. CONCLUSION: Short-term MT provides a significant improvement in patients with knee OA. MT is well tolerated and causes no serious complications.

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