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Learning oriented physiotherapy (LOP) in anxiety and depression: an 18 months multicentre randomised controlled trial (RCT)
Bratberg G, Leira K, Granan LP, Jonsbu E, Fadnes BL, Thuland SF, Myklebust TA
European Journal of Physiotherapy 2021;23(5):295-304
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIM: Although many patients with anxiety and depression suffer from muscular pain and bodily dysfunctions, body is largely ignored in treatment. The aim of this study was to investigate the effectiveness of Learning Oriented Physiotherapy (LOP), based on recent knowledge about overlapping brain networks and the need of awakening body awareness in order to synchronise body and mind. METHOD(S): Patients with moderate anxiety and/or depression referred to three outpatient psychiatric clinics in Norway during October 2014 to January 2016 were invited to participate. Of eligible patients, 42 were randomised to LOP and 39 to standard psychiatric treatment (controls). Self-reports of anxiety and depression (HADS), health-related quality of life (EQ-5D-5L) and global health (EQ-VAS) were recorded every 6 months from baseline (T1) to 18 months after (T4). Mixed linear model (MLM) analysis was used to estimate overall differences between groups. RESULT(S): After 1 year of follow-up, LOP participants reported higher quality of life and perceived global health than controls. At the end of the trial, there were no mean differences in health outcomes between groups, but LOP participants showed an overall faster rate of recovery than controls. CONCLUSION(S): LOP may be as effective as conventional therapies for patients with moderate anxiety and depression.

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