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A controlled clinical trial on the effects of exercise on lower urinary tract symptoms in women with multiple sclerosis
Silva Ferreira AP, de Souza Pegorare ABG, Miotto Junior A, Salgado PR, Medola FO, Christofoletti G
American Journal of Physical Medicine & Rehabilitation 2019 Sep;98(9):777-782
clinical trial
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: The aim of the study was to investigate the effects of two pelvic floor exercise programs on lower urinary tract symptoms and quality of life in participants with multiple sclerosis. DESIGN: This is a prospective, single-blind, clinical trial. SETTINGS: The study used a community rehabilitation program within a large metropolitan health service. PARTICIPANTS: Thirty women in moderate stage of multiple sclerosis were referred for outpatient rehabilitation. INTERVENTIONS: In a period of 6 mos, participants underwent a pelvic floor exercise program, associated or not with vaginal electrotherapy. MAIN OUTCOMES: The main outcomes are overactive bladder, perineal contraction, and quality of life. RESULTS: The findings showed benefits of both programs on overactive bladder and quality of life. Participants undergoing exercise plus electrotherapy presented greater improvement on contraction of the perineal musculature and quality of life. CONCLUSIONS: Six months of exercise provided benefits on lower urinary tract symptoms and quality of life in women with multiple sclerosis. Electrical stimulation potentiated the improvement on perineal musculature and quality of life. This trial was registered prospectively with the clinical trials register, ID BR-287q65 (http://www.ensaiosclinicos.gov.br/rg/RBR-287q65/).

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