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Effect of shoulder immobilization on wound seroma and shoulder dysfunction following modified radical mastectomy: a randomized prospective clinical trial
Dawson I, Stam L, Heslinga JM, Kalsbeek HL
The British Journal of Surgery 1989 Mar;76(3):311-312
clinical trial
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Wound seroma and shoulder dysfunction are the most frequent complications of a mastectomy. To prevent the development of a frozen shoulder it seems justifiable to recommend post-operative exercises. However, early shoulder exercises may have a deleterious effect on wound healing and seroma formation. The purpose of this study was to determine the effect of temporary shoulder immobilization on would seroma and shoulder dysfunction following modified radical mastectomy.

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