OBJECTIVE: This study aimed to compare the effects between low- versus medium-energy radial extracorporeal shock wave therapy on knee osteoarthritis (KOA). METHOD: Forty-five patients (26 women and 19 men) aged 45 to 55 years with grade 2 KOA were randomly assigned into the following three groups (all n = 15): group A received low-energy radial shock wave therapy (2,000 shock/session (10 Hz), energy flux density (EFD) 0.02 mJ/mm2) with strengthening exercises once per week for 4 weeks; group B received medium-energy radial shock wave therapy (2,000 shock/session (10 Hz), EFD 0.178 mJ/mm2) with strengthening exercises once per week for 4 weeks; and group C (control group) received sham shock wave therapy with strengthening exercises once per week for 4 weeks. Severity of pain was determined using the visual analogue scale, and knee physical function was assessed using the Arabic version of the knee injury and osteoarthritis outcome score physical function short form. Knee proprioception was measured before and after the treatment programme using an isokinetic dynamometer. RESULTS: The within-group analysis showed significant differences in severity of pain, knee physical function, and knee proprioception in groups A and B before and after the treatment programme (p < 0.05). The between-group analysis showed significant differences in all variables after treatment, with more significant differences observed in group B than in groups A and C (p < 0.05). CONCLUSION: Low- and medium-energy radial shock wave therapies are effective modalities for the treatment of KOA, with medium-energy radial shock wave therapy being superior to low-energy radial shock wave therapy.

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