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| Preoperative pelvic floor muscle exercise does not reduce the rate of postprostatectomy incontinence: evidence from a meta-analysis and a systematic review |
| Cheng H, Wang Y, Qi F, Si S, Li X, Chen M |
| Translational Andrology and Urology 2020 Oct;9(5):2146-2156 |
| systematic review |
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BACKGROUND: A growing number of researches suggested that preoperative pelvic floor muscle exercise (PFME) was beneficial for urinary incontinence (UI) after a prostatectomy. However, these studies are debatable and inconclusive. Hence, this article aimed to determine whether PFME improves UI after a radical prostatectomy (RP). METHODS: PubMed, Embase, Medline and Cochrane Library were searched for articles published from 2014 to October 2019 based on the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA). This study was evaluated based on the Oxford Evidence-Based Medicine Center. A total of 1,269 subjects (experimental group: 628, control group: 641) in 18 studies met the inclusion criteria. In 18 studies, enough quantitative data on postoperative incontinence were available for meta-analysis. UI was analyzed at 1, 3, 6 and 12 months and all comparative studies were pooled using fixed and random effects models. Contour-enhanced funnel plots were used to assess publication bias. RESULTS: Pooled data revealed a total of 1,269 UI patients that underwent preoperative PFME, including PFME (N = 628, 49.48%) and control group (N = 641, 50.51%). There was no significant difference in the postoperative incontinence rates at 1 month (RR 0.85, 95% CI 0.66 to 1.09, p = 0.031, I2 = 62.4%), 6 weeks (RR 0.95, 95% CI 0.85 to 1.05, p = 0.618, I2 = 0.0%), 3 months (RR: 0.92, 95% CI 0.63 to 1.34, p = 0.000, I2 = 83.2%), 6 months (RR 0.86, 95% CI 0.69 to 1.08, p = 0.364, I2 = 8.4%) or 12 months (RR 0.83, 95% CI 0.47 to 1.47, p = 0.596, I2 = 0.0%) after operation. CONCLUSIONS: Contrary to previous work, the results presented here indicated that preoperative PFME protocols did not reduce the rate of UI. Further high-quality randomized controlled trials are necessary in the future to verify these findings.
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