BACKGROUND: Exercise has been recommended as an important intervention for reducing adiposity in children and adolescents with overweight and obesity. OBJECTIVE: Determine whether inter-individual differences exist in relation to exercise-induced changes in adiposity among children and adolescents with overweight and obesity. METHODS: Meta-analysis of randomized controlled aerobic exercise trials and body mass index (BMI) in kg/m2. Change outcome standard deviations were pooled using the inverse-variance heterogeneity model. RESULTS: Twenty-eight studies (1,185 participants) were included. Inter-individual differences in BMI were -0.1 (95% compatibility interval -0.7 to 0.7). The 95% prediction interval for inter-individual responses in a future study was -2.9 to 2.9. The probability of a clinically meaningful difference in variability was 29% (possibly clinically important) in favour of controls versus exercisers. CONCLUSIONS: Inter-individual differences for BMI in kg/m2 were not observed as a result of aerobic exercise in children and adolescents with overweight and obesity.

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