PURPOSE: The primary aim of this systematic review was to assess the current evidence on the economic evaluations of physical rehabilitation interventions in older adults with hip and/or knee osteoarthritis (OA). MATERIAL(S) AND METHOD(S): PubMed, Scopus, Embase, Web of Science, CENTRAL, PEDro, and Econlit were searched from January 1, 1995, through April 14, 2019. This study was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline statement. Methodological quality assessment was performed using the Drummond's checklist. RESULT(S): Of 1,341 identified tips, 20 studies met the eligibility criteria. Cost-effectiveness analysis (60%) and cost-utility analysis (20%) were the main approaches adopted. Except two studies were based on an observational study, other studies were based on randomized controlled trials. An assessment of these studies demonstrated that physical rehabilitation interventions compared to usual care or surgical procedures result in cost saving and improving the quality of life. CONCLUSION(S): Physical rehabilitation interventions were cost-effectiveness and should be considered by health policy-makers and insurers for the management of patients with knee and hip OA. Furthermore, future studies will need to evaluate the cost-effectiveness of other physical rehabilitation interventions such as physiotherapy and orthotic approaches for definitive conclusions. REGISTRATION CODE: CRD42019123478.

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