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Effects of an "active-workstation" cluster RCT on daily waking physical behaviors
Arguello D, Thorndike AN, Cloutier G, Morton A, Castaneda-Sceppa C, John D
Medicine and Science in Sports and Exercise 2021 Jul;53(7):1434-1445
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

PURPOSE: This study aimed to evaluate the effects of sit-to-stand and treadmill desks on sedentary behavior during a 12-month, cluster-randomized multicomponent intervention with an intent-to-treat design in overweight office workers. METHODS: Sixty-six office workers were cluster-randomized into a control (n = 21; 8 clusters), sit-to-stand desk (n = 23; 9 clusters), or treadmill desk (n = 22; 7 clusters) group. Participants wore an activPAL accelerometer for 7 d at baseline, month 3, month 6, and month 12 and received periodic feedback on their physical behaviors. The primary outcome was total daily sedentary time. Exploratory outcomes included total daily and workplace sedentary, standing and stepping time, and the number of total daily and workplace sedentary, standing, and stepping bouts. Intervention effects were analyzed using random-intercept mixed linear models accounting for repeated measures and clustering effects. RESULTS: Total daily sedentary time did not significantly differ between or within groups after 12 months. Month 3 gains were observed in total daily and workplace standing time in both intervention groups (sit-to-stand desk mean delta +/- SD 1.03 +/- 1.9 h/d and 1.10 +/- 1.87 h at work; treadmill desk mean delta +/- SD 1.23 +/- 2.25 h/d and 1.44 +/- 2.54 h at work). At month 3, the treadmill desk users stepped more at the workplace than the control group (mean delta +/- SD 0.69 +/- 0.87 h). Month 6 gains in total daily stepping were observed within the sit-to-stand desk group (mean delta +/- SD 0.82 +/- 1.62 h/d), and month 3 gains in stepping at the workplace were observed for the treadmill desk group (mean delta +/- SD 0.77 +/- 0.83 h). These trends were sustained through month 12 in only the sit-to-stand desk group. CONCLUSIONS: Active-workstation interventions may cause short-term improvements in daily standing and stepping. Treadmill desk users engaged in fewer sedentary bouts, but sit-to-stand desks resulted in more frequent transitions to upright physical behaviors.

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