PURPOSE: Studies suggest that additional exercise (Ex) training beyond "usual care" increases peak VO2 in people post-heart transplant (HTx); however, no recent studies have quantified improvements or compared moderate-intensity aerobic Ex (MOD) to high-intensity interval training (HIIT). The purpose of this study was to quantify improvements in VO2 for patients post-HTx undergoing additional Ex training and compare effectiveness of MOD to HIIT. METHODS: Inclusion criteria were: randomized clinical trials, systematic reviews, or meta-analyses published between 2008 to 2018, subjects post-HTx, participated in an aerobic Ex program beyond usual care, and reported peak VO2. RESULTS: A total of 242 records were obtained and 7 randomized clinical trials were reviewed. The average PEDro score was 4.86 (range 2 to 7). The within-group weighted mean difference (WMD) in peak VO2 comparing baseline to post-training for the Ex group 3.3 (0.5) ml/kg/min and for the control group -0.2 (0.2) ml/kg/min. The between-group WMD in peak VO2 3.5 (7.9) ml/kg/min, Hedge's g 0.606 (95% confidence intervals 0.337 to 0.874), p < 0.001, favoring Ex. Comparison between Ex protocols indicated that there was no difference between HIIT and MOD (Q = 1.83, p = 0.176). CONCLUSIONS: Physical therapists should challenge patients post-HTx with aerobic Ex that goes beyond usual post-HTx care and should consider incorporating HIIT into the treatment plan or home program to maximize the benefits of rehabilitation when possible.

Full text (sometimes free) may be available at these link(s):      help

• DOI
• PDF locator
• publisher