BACKGROUND: Many studies have investigated the effects of Kinesio Tape on the symptoms of carpal tunnel syndrome (CTS). OBJECTIVES: The present study aimed to review the results of clinical trials on the use of Kinesio Tape to improve CTS symptoms. METHODS: The present systematic review was based on PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) on clinical trials. The keywords "carpal tunnel syndrome, median nerve, Kinesio Tape, and physical therapy" were searched in Embase, PubMed, SID, Magiran, Cochrane Library, Scopus, ScienceDirect, Springer, Ovid, ProQuest, PEDro, and Google Scholar databases. RESULTS: Out of 1,259 articles, only 13 met the requirement for inclusion in the study. The results of 11 articles indicated that the use of Kinesio Tape could significantly reduce CTS symptoms. CONCLUSION: The use of Kinesio Tape reduces CTS symptoms (ie, pain, numbness, and hand function).

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