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| Efficacy of low frequency low intensity pulsed magnetic field on fatigue in persons with multiple sclerosis. A randomized controlled trial |
| Ali AS, Rashad UM, Aboumousa A, el-Sayed MS, Elzanaty MY |
| Journal of Cardiovascular Disease Research 2021;12(5):569-576 |
| clinical trial |
| 4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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BACKGROUND: Fatigue is the most common symptom of multiple sclerosis (MS). It occurs in 75 percent to 95 percent of patients with MS. Fatigue occurs at all stages of the disease. The symptom is not related to the severity or to the duration of MS. AIM:The aim of current study was to investigate the efficacy of pulsed magnetic field on fatigue in persons with multiple sclerosis. METHODS: Thirty persons with multiple sclerosis from both sexes represented the sample of this study. They were recruited from the outpatient clinics, Faculty of Physical Therapy, Cairo University and multiple sclerosis specialized clinic in the Neurology Department, Faculty of Medicine, Cairo University. The person's age ranged from twenty to forty years. They were assigned randomly into two equal groups; the study group (GA) and the control group (GB). The assessment of fatigue is conducted before and after treatment for both groups by Fatigue Severity Scale (FSS) and Fatigue Assessment Scale (FAS). Assessment of multiple sclerosis symptoms was conducted before and after treatment for both groups by Expanded Disability Status Scale (EDSS). Study group (GA) treated by pulsed magnetic field (Low intensity and low frequency) applied on cranium in addition to a selected physical therapy program for fatigue for persons with multiple sclerosis. Control group (GB) treated by the same program of treatment for Fatigue only as the (GA) without pulsed magnetic field. The duration of treatment was six weeks, three times weekly, and day after day. RESULTS: Comparison of the mean value of each variable pre and post treatment in each group revealed a significant improvement in all different parameters in both groups; however comparison between post results of both groups revealed that the study group (GA) showed a significant improvement compared to the control group (GB) in all different variables (p < 0.05 for all). CONCLUSION: Application of pulsed magnetic field with low intensity and low frequency had a positive effect in decreasing MS fatigue.
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