OBJECTIVE: Neurological disorders (ND) are ranked as the leading cause of death and disability around the globe and the escalating burden summons the advancements in the treatment strategies hence this systematic review aimed to fill the knowledge gap regarding the efficacy of robot-assisted physiotherapy (RAPT) for pain management in ND. MATERIALS AND METHOD: Scientific trials were sought by an extensive search via electronic databases mainly PubMed, PEDro and Scopus. Randomized controlled trials published from the year 2014 to April 2021, evaluating the potential effects of RAPT for pain management in ND were included in the review. The quality appraisal of the RCTs was analyzed via Cochrane tool for assessing risk of bias. RESULTS: The majority of the trials reported the effectiveness of RAPT using PARO robot, Armeo spring, Gloreha robot, and robotic Lokomat gait training system in significantly improving pain of ND such as stroke, dementia, phantom syndrome, and spinal cord injuries. CONCLUSION: Large body of evidence suggested RAPT as a potential solution in improving pain of various ND. However, further rigorous trials are necessary to draw conclusive recommendations.

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