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Physical function and health-related quality of life in older adults with or at risk of mobility disability post-discharge: 8-month follow-up of a randomized controlled trial
Sunde S, Hesseberg K, Skelton DA, Ranhoff AH, Pripp AH, Aaronaes M, Brovold T
Journal of Aging and Physical Activity 2022 Jun;30(3):404-410
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The objective of this study was to evaluate physical function and health-related quality of life 4 months after the cessation of a 4-month exercise intervention in 89 older adults after discharge from hospital. Linear mixed regression models were used to evaluate between-group differences. Data were analyzed according to the intention-to-treat principle. There was no statistically significant between-group difference in the Short Physical Performance Battery (mean difference 0.5 points, 95% confidence interval (-0.6 to 1.5), p = 0.378). There was a statistically significant difference in favor of the intervention group in functional capacity (the 6-min walk test; mean difference 32.9 m, 95% confidence interval (1.5 to 64.3), p = 0.040) and physical health-related quality of life (physical component summary of medical outcome Study 36-Item Short-Form Health Survey; mean difference 5.9 points, 95% confidence interval (2.0 to 9.7), p = 0.003). Interventions aiming to maintain or increase physical function and health-related quality of life should be encouraged in this population.

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