OBJECTIVE: To explore the clinical effect of gait motor imagination therapy on improving motor function of stroke patients with hemiplegia. METHODS: A total of 120 stroke patients admitted to University of Chinese Academy of Sciences Shenzhen Hospital (Guang Ming) from January 2018 to January 2021 were selected and divided into intervention group and control group by random number table method. The control group was treated with conventional rehabilitation nursing therapy, and the intervention group was treated with conventional rehabilitation nursing combined with gait motor imagination therapy. After excluding the number of shedding cases, 59 cases were found in the intervention group and 56 cases in the control group. Fugl-Meyer scale and QLQ-C30 scale were used to evaluate motor function and quality of life in 2 groups, and the correlation between them was analyzed. Serum levels of BDNF and S100B were determined by ELISA. RESULTS: With the extension of intervention time, the improvement effect of Fugl-Meyer score, QLQ-C30 scale score, BDNF and S100B content in 2 groups was better (p < 0.05). At 5 and 10 weeks after intervention, Fugl-Meyer score and the contents of BDNF and S100B in QLQ-C30 scale score in the intervention group were better than those in the control group (p < 0.05). There was a significant positive correlation between motor function and quality of life (p < 0.05). CONCLUSION: Gait motor imaging therapy can effectively improve the patients' motor function, neurobiochemical indexes and quality of life, and the improvement of motor function is helpful to promote the improvement of patients' quality of life.

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