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Comparison of quadriceps and hamstring muscle strength after exercises with and without blood flow restriction following anterior cruciate ligament surgery: a randomized controlled trial [with consumer summary]
Vieira de Melo RF, Cohen M, Komatsu WR, de Freitas MS, Vieira de Melo ME
Journal of Rehabilitation Medicine 2022 Nov 1;54:jrm00337
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Muscle mass loss occurs following anterior cruciate ligament reconstruction surgery. OBJECTIVE: To compare the gain in muscle strength in the quadriceps and hamstring muscles in patients following anterior cruciate ligament reconstruction surgery, using exercises with and without blood flow restriction. METHODS: The isometric muscle strength of subjects' knee extension and flexion was evaluated using a digital hand dynamometer, and the physical function of the knee was evaluated using the Lysholm, Knee and Osteoarthritis Outcome Score, and International Knee Documentation Committee questionnaires. RESULTS: Statistical differences were observed in the quadriceps, with an increase in muscle strength (p < 0.01) after 12 weeks, and in the hamstrings (p < 0.01) after 8 and 12 weeks. There was a significant increase in the Lysholm questionnaire score (p < 0.01) after 8 and 12 weeks, a decrease in the Knee and Osteoarthritis Outcome Score pain questionnaire (p < 0.01) after 4 weeks, symptoms and daily activities (p < 0.01) after 8 and 12 weeks, quality of life (p < 0.01) after 12 weeks, and an increase in the International Knee Documentation Committee questionnaire score (p < 0.01) after 8 and 12 weeks. CONCLUSION: After anterior cruciate ligament surgery, exercises with blood flow restriction proved more efficient for improving the muscle strength of the quadriceps and hamstrings, and the physical function of the knee.

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