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| Effects of multimodal rehabilitation on the activities of daily living, quality of life, and burden of care for patients with Parkinson's disease: a randomized control study |
| Choi H-S, Cho S-H |
| Healthcare 2022 Sep;10(10):1888 |
| clinical trial |
| 5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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BACKGROUND: Parkinson's disease reduces patients' function, activities of daily living, and quality of life, and increases their guardians' burden of care. This study verified the effectiveness of a multimodal rehabilitation programme for patients with Parkinson's disease. TRIAL DESIGN: This study was a multicentre parallel randomised controlled, single-blind, trial conducted in three hospitals in Korea. METHODS: A central randomisation centre used computer generated tables to randomly allocate 60 of 75 patients with Parkinson's disease who fulfilled the study requirements into experimental (n = 30; multimodal rehabilitation; consisting of daily living training, guardian education, home environment modification, fine muscle exercise, balance training, and training using auxiliary tools performed 50 min per session, twice a week, in 10 sessions) and control (n = 30; traditional rehabilitation; consisting of task-oriented training, joint exercise, and daily living training performed 50 min per session, twice a week, in 10 sessions) groups. RESULTS: Multimodal rehabilitation for Parkinson's disease significantly improved the activities of daily living (p < 0.01) and quality of life of patients (p < 0.001) and eased the guardians' burden of care (p < 0.001). CONCLUSIONS: Multimodal rehabilitation is suggested to improve activities of daily living, quality of life of patients with Parkinson's disease, and reduce the burden of care of their guardians.
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