BACKGROUND AND AIM: Polycystic ovary syndrome (PCOS) is associated with an increased cardiovascular disease (CVD) risk. Pdis and QTdis are simple and useful electrocardiographic markers that may be used in the prediction of the risk of adverse cardiovascular events in PCOS patients. The main purpose of present study was to evaluate the effect of eight weeks of moderate-intensity aerobic training (MICT) on Pdis and QTdis as biomarkers of adverse cardiovascular events in women with PCOS. METHODS: 30 females with PCOS aged between 18 and 40 years were randomly divided into an eight-week MICT and a control group. The MICT program included eight weekly sessions (three sessions a week). Electrocardiography was performed the day before the intervenion, and 48 hours after the last exercise session. A cardiologist evaluated all parameter measurements st. Statistical analysis was conducted by tes t-test using SPSS software (version 23). P less than 0.05 was considered statistically significant. RESULTS: After the eight-week intervention, a significant reduction in QTdis, QTcdis, weight, and BMI was observed in the MICT group (p < 0.01) but not in the control group (p > 0.05). Regarding Pdis, no significant change was observed before and after intervention in both groups (p > 0.05). CONCLUSION: These findings demonstrated that eight weeks of MICT in PCOS patients could be prescribed to prevent adverse cardiovascular events in women with PCOS.

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