PURPOSE: After a total knee arthroplasty (TKA), ensuring rehabilitation is continued at home is essential for a successful recovery. The aim of this randomized clinical trial (NCT04155957) was to demonstrate the safety and efficacy of an interactive telerehabilitation system (ReHub) to guide and provide feedback during exercise in the postoperative period of a fast-track TKA program. METHODS: Fifty-two patients who underwent TKA were randomized to intervention (n = 26) or control (n = 26). Upon discharge, they followed a 4-week plan of 5 daily exercises and up to 10 physiotherapy home visits. The intervention group performed exercises with ReHub autonomously, control did not use any auxiliary device. Data were collected (1) on the day of discharge, (2) after 2 weeks and (3) after 4 weeks. RESULTS: Telerehabilitation patients showed higher adherence to exercise (p = 0.002) and greater quadriceps strength (p = 0.028). No significant differences between groups were found in other outcomes. Only 1 adverse event was linked to ReHub. Patients gave the platform high System Usability Scale scores (83/100). CONCLUSION: Interactive telerehabilitation with ReHub during a post-TKA exercise program is effective, safe, and well-received by patients. It provides real-time performance feedback and ensures communication. Quadriceps strength and adherence to the exercise plan are improved with ReHub.

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