BACKGROUND: To compare the therapy effects following the aerobic exercise combined with resistance exercise training (AET plus RET) and common care treatment for patients with breast cancer. METHODS: Articles about the effects of AET plus RET on the breast cancer patients in 4 online databases were searched. The differences of cardiopulmonary function, blood pressure, blood lipid, and body mass index between the AET plus RET treatment and the usual care treatment were compared. RESULTS: Totally, 8 articles were involved into the meta-analysis. The qualities of the 8 articles were medium. The combination results showed that AET plus RET increased the VO2peak (weighted mean difference (WMD) 2.93 mL/kg/min; 95% CI 0.38 to 5.49; p = 0.02) and VO2max (WMD 6.98 mL/kg/min; 95% CI 2.04 to 15.92; p = 0.01), demonstrating its improving effects in cardiopulmonary function. Moreover, the AET plus RET decreased the TG (WMD -57.95 mg/dL; 95% CI -112.25 to -3.64; p = 0.04), demonstrating its improving effects in blood lipid. While or the HRpeak, RERpeak, systolic blood pressure, diastolic blood pressure, high-density lipoprotein cholesterol, and body mass index, there are no significant differences between the AET plus RET and usual care treatment (p < 0.05). CONCLUSION: Our results demonstrated that AET plus RET can significantly improve the cardiopulmonary function and blood lipid for breast cancer patients.

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