INTRODUCTION: COVID-19 patients perceive a lot of stress and suffer from psychological symptoms including depression, stress and anxiety. Because these patients are required to comply with quarantine conditions, remote training can be used for these patients. Therefore, this study was conducted with the aim of investigating the effect of remote training of stress management in a cognitive-behavioral way on the psychological symptoms of COVID-19 patients. MATERIALS AND METHODS: In this randomized clinical trial, the research population was all the patients with COVID-19 referred to the Dr. Garazi hospital in Isfahan city in the winter of 1400. 70 people were selected by available sampling method and divided into two intervention and control groups (35 people) by limited randomization method. For the intervention group, remote training program on stress management was implemented in five sessions of 60 minutes in two weeks. The control group did not receive training. Psychological symptoms were measured before and after the training sessions using the DASS-21 questionnaire. The data were analyzed with SPSS21 software and at two levels of descriptive and inferential statistics and by performing chi-square tests, analysis of variance, independent and paired ttest, and analysis of covariance. RESULTS: Remote training of stress management in a cognitive-behavioral way has had a significant effect on all dimensions of psychological symptoms of COVID-19 patients in the intervention group and has reduced them in the intervention group. (p <= 0.05). CONCLUSION: Based on the results, this method of training can improve the psychological symptoms of COVID-19 patients. Considering the possibility of easy and comprehensive use of distance education, it is recommended to use this method of teaching patients in similar pandemic conditions.

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