BACKGROUND: Increased inflammation and oxidative stress are the main causes of many common diseases of old age. OBJECTIVES: The aim of the present study was to evaluate the effects of combined training on inflammatory and oxidative markers and the general-social health of overweight older male adults. METHODS: In this quasi-experimental study, 40 overweight older male adults with an age range of 60 to 75 years were purposefully selected and randomly divided into two training and control groups. The training program included aerobic, resistance, and balance training for eight weeks and three days a week. Study variables were measured 48 hours before and after the intervention. The statistical analysis of the data was done by two-way repeated measure analysis of variance and Tukey's post hoc tests at a significance level of p <= 0.05. RESULTS: After eight weeks of combined training, levels of TNF-alpha (p <= 0.01), hs-CRP (p <= 0.03), and MDA (p <= 0.01), the mass of fat (p <= 0.04) decreased, while the level of superoxide dismutase (p <= 0.01) and the score of social health (p <= 0.01) increased significantly. CONCLUSIONS: It seems that combined training in the elderly is a suitable option for modulating and regulating inflammatory and oxidative biomarkers and improving general social health.

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