BACKGROUND AND OBJECTIVES: In a woman who experienced menopause, there is a decrease in the strength of the muscle due to hormonal changes and because of several changes related to the hormones that occur in the body, it affects the body's BMI which then affects to daily life. Physiotherapy is an effective way of reducing the majority of difficulties while doing daily activities and thereby improving overall health. The study aims to determine how the structured exercise protocol affects a muscle imbalance of hamstrings and quadriceps in postmenopausal obese women. METHODOLOGY: This research study was carried out on 50 females who experienced menopause and were between the age group 50 to 60 years the inclusion criteria were satisfied by them and they were divided into 2 groups randomly. Pre-interventional and post-interventional measurements were taken by Modified Sphygmomanometer, by 90 to 90 SLR test, range of knee joints by goniometer also pain was assessed. Group A (the control group) received the treatment which included hot moist therapy along with hamstrings active stretching, isometric exercises for both hamstrings and quadriceps and quadriceps strengthening and Group B received the treatment which included mulligans technique for hamstrings and for quadriceps muscle, MET technique was used. Both groups received the treatment for 6 weeks. RESULTS: Statistically significant changes (with p-value < 0.05) were seen in the pre and post-interventional measurements. But the value of the mean shows more progress in group B compared to group A. Research CONCLUSIONS: Both protocols are useful in the treatment of muscle imbalance in quadriceps and hamstrings in postmenopausal obese women but the structured exercise protocol is more effective than the conventional protocol for muscle imbalance of quadriceps and hamstrings in postmenopausal obese women.

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