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| Comparative study of the efficacy of hyaluronic acid, dry needling and combined treatment in patellar osteoarthritis-single-blind randomized clinical trial |
| Saornil JV, Sanchez-Mila Z, Campon Chekroun AM, Baraja Vegas L, Vicente Mampel J, Frutos Llanes R, Barragan Casas JM, Rodriguez-Sanz D |
| International Journal of Environmental Research & Public Health 2022 Sep;19(17):10912 |
| clinical trial |
| 4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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BACKGROUND: Osteoarthritis of the knee is one of the most common ailments worldwide, and pain management of this condition is critical. METHODS: A multicentre randomized controlled trial RCT with three months of follow-up, conducted in parallel groups: hyaluronic acid (HA), dry needling (DN) and ultrasound (US) and isometrics of quadriceps. 60 participants took part in the RCT who were diagnosed with osteoarthritis (Grade 3) of the knee by MRI and active adults (age 23.41 +/- 1.68 years; height 1.79 +/- 0.08 m; body mass 78.33 +/- 9.03 kg; body mass index (BMI) 24.14 +/- 1.45 kg/m2). After the assigned intervention, VAS, WOMAC, IPAQ and the Star Excursion Balance test were measured at baseline. At 24 h, 15 days, 30 days, 90 days and 180 days follow-up, all variables were measured again. RESULTS: Comparing statistically significant differences between groups, VAS scores were significant at post-test measurement (HA versus US plus isometric and DN versus US plus isometric) at 24 h (HA versus DN), at 15 days (HA versus US plus isometric and DN versus US plus isometric) and at 1 month (US plus isometric versus HA and US plus isometric versus DN). CONCLUSIONS: There is an improvement in pain intensity in knee osteoarthritis in the short term in patients undergoing DN and conventional US plus isometric treatment, but in the long term the HA group shows an improvement in pain intensity. There is also a significant difference in the improvement of knee function at different phases of the study in the various intervention groups. The combination of DN and HA in clinical practice is the best option for the treatment of osteoarthritis.
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