Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

Effects of exercise training in patients with lung cancer during chemotherapy treatment
Rehman M, Ahmad U, Waseem M, Ali B, Tariq MI
The Malaysian Journal of Medical Sciences 2023 Apr;30(2):141-152
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: Yes; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Cancer is the second greatest cause of death and disability after cardiovascular disease. OBJECTIVE: To determine the effects of exercise training in patients with lung cancer during chemotherapy treatment. METHODS: A randomised clinical trial was conducted in Shaukat Khanum Memorial Cancer Hospital and Institute of Radiotherapy and Nuclear Medicine (IRNUM) Peshawar. A total of 40 participants were randomly divided into two groups: (i) the Experimental group (EG, n = 20) and (ii) Control group (CG, n = 20). Both groups received exercise training for 4 weeks, with five sessions per week. The EG received pulmonary rehabilitation and aerobic training. The CG received only pulmonary rehabilitation. Both groups were evaluated at baseline and after 6 weeks through Mindful Attention Awareness Scale (MAAS) Urdu version, Six Minute Walk Test (6MWT), digital spirometry, Borgs scale, Hospital Anxiety and Depression Scale (HADs) and Visual Analogue Scale (VAS). RESULTS: Both the EG and CG showed significant improvement in MAAS scores at post-study with a (p < 0.001). The scores of 6MWT were improved significantly in both groups after intervention with a (p = 0.001). The patient's anxiety scores were significantly improved in both groups after intervention with a (p < 0.001), while depression scores were also improved considerably between the two groups at post-level with a (p < 0.001). Regarding spirometry value, both groups showed significant improvement after intervention for forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC (p < 0.001). Both groups show significant differences in patient pain intensity and dyspnea at post-level with p < 0.001. CONCLUSION: This study concluded that pulmonary rehabilitation along with aerobic training can be more effective than pulmonary rehabilitation alone for patients with lung cancer during chemotherapy treatment.

Full text (sometimes free) may be available at these link(s):      help