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Quantitative research for improving respiratory muscle contraction by breathing exercise
Qiying Y, Yinxiang S
Zhonghua Yi Xue Za Zhi [Chinese Medical Journal] 1996;109(10):771-775
clinical trial
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To investigate the effects of breathing exercise on chronic obstructive pulmonary disease (COPD). PATIENTS AND METHODS: 324 patients stable COPD were randomly assigned to either the breathing exercise group (group 1) or control group consisting of placebo (group II). The maximum respiratory pressure (320 cases) and transdiaphragmatic pressure (129 cases) were monitored via RMS-I and type-2 pressure measurements. The breathing exercises were taught and checked by experienced specialists periodically. Comparison was made between group I and group II using maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), diaphragmatic pressure (Pdi) and maximum transdiaphragmatic pressure (Pdimax) after 1 to 20 months. RESULTS: In group I MIP increased by 30.42%, MEP 32.10%, Pde 30.94% and Pdimax 65.59% (p < 0.001). No significant changes were observed in group II given the placebo. The MIP, MEP, Pdi and Pdimax were 6.95%, 2.92%, 14.63% and 9.05% respectively (p > 0.05). CONCLUSIONS: Breathing exercise has a potent and long lasting effect on respiratory muscle contraction. The methods mentioned above can be used as standard quantitative index for contractile properties of respiratory muscle.

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